US Prohibits the Extralabel Use of Cephalosporin

The FDA claims that this rule will help further protect consumers against antimicrobial-resistant strains of zoonotic foodborne bacterial pathogens.

By law, FDA may issue a prohibition order if evidence shows that extralabel use of a drug in food-producing animals has caused, or is likely to cause, a public health risk.

In this case, the FDA gathered evidence showing that the extralabel use of cephalosporins in food-producing animals is likely to contribute to the emergence of resistance and compromise human therapies.

Given the importance of the cephalosporin class of drugs for treating disease in humans, FDA believes that preserving the effectiveness of such drugs is critical. Therefore, they believes it is necessary to take action to limit the extent to which extralabel use of cephalosporins in food-producing animals may be contributing to the emergence of resistant variants.

According to the FDA the prohibition of extralabel use of cephalosporin antimicrobial drugs in food-producing animals will protect the public health by preserving the effectiveness of cephalosporin-class drugs for the treatment of human infections.

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