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Peri-Weaning Diarrhoea

Copyright © NADIS 2002 - 2007 Peri-weaning (or post-weaning) diarrhoea is becoming a significant and increasing disease of calves on many farms

What is peri-weaning diarrhoea?

Peri-weaning diarrhoea is an apparently new syndrome in calves around the time of weaning (usually, but not always, after weaning). The cause of the disease is unknown, infectious agents, managemental, environmental and nutritional factors have all been implicated.

The diarrhoea is usually first seen fairly soon after group housing, particularly if the animals were previously kept in outdoor hutches. However, in some outbreaks diarrhoea can begin up to two weeks before weaning.

Clinical Signs

  • Profuse watery grey diarrhoea.
  • Most calves affected, but death usually rare
  • The calves tend to be bright and continue eating
  • Dehydration tends to be moderate
  • Pot-bellied appearance common in ‘recovered’ calves
  • Reduced growth rate, and uneven batches of calves has significant economic effect.
  • Significant faecal staining of the coat and appearance of ‘ill thrift’.


  • On the clinical signs described above
  • Usually a diagnosis of ‘exclusion’, i.e. other diseases ruled out by investigation


  • Treatment, except for electrolytes to treat dehydration, is often ineffective, with the duration of the disease seeming to depend on the age at which it developed (younger animals tend to have more persistent diarrhoea)..
  • Many antibiotics have been tried but none are routinely effective. Ask your vet for further advice on


The cause is unknown so no specific prevention programme has been developed. However several management and nutritional factors have been implicated, and preventing these has reduced the incidence of peri-weaning diarrhoea on many farms: Management: Avoid abrupt weaning and ensure calves get colostrum for at least the first week after birth. Nutritional: Avoid the use of calf pellets that rapidly ferment in the rumen, use slower fermenting coarse mixes. Also avoid products containing heat treated soya.

Copyright © NADIS 2002 - 2007
NADIS (National Animal Disease Information Service) is a network of 40 veterinary practices and 6 veterinary colleges monitoring diseases in cattle, sheep and pigs in the UK, including BPEX, EBLEX, HCC, QMS, Elanco Animal Health, MLC and Merial

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